Mouse (Mus musculus)

Top 500 InterPro hits

No.	InterPro name	Number of genes	Number of Ensembl hits	No.	InterPro name	Number of genes	Number of Ensembl hits
1	IPR017452 GPCR, rhodopsin-like superfamily	1669	2069	251	IPR000203 GPS domain	32	275
2	IPR000276 GPCR, rhodopsin-like, 7TM	1588	10894	252	IPR018499 Tetraspanin	31	90
3	IPR000725 Olfactory receptor	1114	6303	253	IPR000471 Interferon alpha/beta/delta	31	164
4	IPR007110 Immunoglobulin-like	817	3817	254	IPR002018 Carboxylesterase, type B	31	56
5	IPR007087 Zinc finger, C2H2	708	16566	255	IPR001627 Semaphorin/CD100 antigen	31	279
6	IPR015880 Zinc finger, C2H2-like	697	12849	256	IPR004046 Glutathione S-transferase, C-terminal	31	58
7	IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx	657	859	257	IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I	31	33
8	IPR013106 Immunoglobulin V-set	617	1114	258	IPR018979 FERM, N-terminal	31	118
9	IPR000719 Protein kinase, catalytic domain	512	2903	259	IPR007111 NACHT nucleoside triphosphatase	31	75
10	IPR002290 Serine/threonine- / dual-specificity protein kinase, catalytic domain	506	1333	260	IPR000253 Forkhead-associated (FHA) domain	30	183
11	IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain	506	3095	261	IPR002448 Odour-binding protein	30	223
12	IPR020635 Tyrosine-protein kinase, catalytic domain	488	1240	262	IPR004045 Glutathione S-transferase, N-terminal	30	60
13	IPR003599 Immunoglobulin subtype	465	3766	263	IPR000306 Zinc finger, FYVE-type	30	124
14	IPR003596 Immunoglobulin V-set, subgroup	404	759	264	IPR001173 Glycosyl transferase, family 2	30	51
15	IPR001909 Krueppel-associated box	354	2231	265	IPR001073 Complement C1q protein	29	318
16	IPR013098 Immunoglobulin I-set	302	2639	266	IPR000873 AMP-dependent synthetase/ligase	29	104
17	IPR013151 Immunoglobulin	294	1038	267	IPR018159 Spectrin/alpha-actinin	29	1247
18	IPR001356 Homeodomain	281	1867	268	IPR002345 Lipocalin	29	182
19	IPR001841 Zinc finger, RING-type	281	1254	269	IPR006026 Peptidase, metallopeptidase	29	48
20	IPR001680 WD40 repeat	262	7948	270	IPR003604 Zinc finger, U1-type	29	191
21	IPR001849 Pleckstrin homology domain	256	2250	271	IPR004020 DAPIN domain	29	117
22	IPR017986 WD40-repeat-containing domain	235	742	272	IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal	29	75
23	IPR000504 RNA recognition motif domain	234	3339	273	IPR006073 GTP binding domain	29	120
24	IPR003598 Immunoglobulin subtype 2	234	2720	274	IPR002402 Cytochrome P450, E-class, group II	28	109
25	IPR004072 Vomeronasal receptor, type 1	232	916	275	IPR004843 Metallophosphoesterase domain	28	55
26	IPR020683 Ankyrin repeat-containing domain	226	592	276	IPR006187 Claudin	28	122
27	IPR002110 Ankyrin repeat	224	7987	277	IPR002165 Plexin	28	104
28	IPR018249 EF-HAND 2	219	992	278	IPR001879 GPCR, family 2, extracellular hormone receptor domain	28	241
29	IPR006907 Domain of unknown function DUF622	212	319	279	IPR017448 Speract/scavenger receptor-related	28	173
30	IPR000210 BTB/POZ-like	210	803	280	IPR001190 Speract/scavenger receptor	28	544
31	IPR001452 Src homology-3 domain	203	2892	281	IPR006687 Small GTPase superfamily, SAR1-type	28	48
32	IPR000742 Epidermal growth factor-like domain	200	1902	282	IPR001878 Zinc finger, CCHC-type	28	260
33	IPR007960 Mammalian taste receptor	197	206	283	IPR001895 Guanine-nucleotide dissociation stimulator CDC25	28	248
34	IPR001611 Leucine-rich repeat	193	1178	284	IPR006594 LisH dimerisation motif	27	111
35	IPR003961 Fibronectin, type III	187	6514	285	IPR002972 Prostaglandin D synthase	27	221
36	IPR011511 Variant SH3	180	658	286	IPR004000 Actin-like	27	274
37	IPR003671 Spindlin/spermiogenesis-specific protein	178	549	287	IPR017940 ABC transporter, integral membrane type 1	27	86
38	IPR006210 Epidermal growth factor-like	177	3107	288	IPR003954 RNA recognition motif domain, eukaryote	27	117
39	IPR003591 Leucine-rich repeat, typical subtype	173	2698	289	IPR000233 Cadherin, cytoplasmic domain	27	38
40	IPR018957 Zinc finger, C3HC4 RING-type	169	403	290	IPR000301 Tetraspanin, subgroup	27	260
41	IPR013684 Mitochondrial Rho-like	169	343	291	IPR000569 HECT	27	174
42	IPR001828 Extracellular ligand-binding receptor	168	264	292	IPR007237 CD20-like	27	57
43	IPR001806 Small GTPase superfamily	168	1668	293	IPR000418 Ets	27	544
44	IPR006689 Small GTPase superfamily, ARF/SAR type	167	492	294	IPR001400 Somatotropin hormone	27	158
45	IPR001254 Peptidase S1/S6, chymotrypsin/Hap	165	825	295	IPR002067 Mitochondrial carrier protein	27	249
46	IPR013069 BTB/POZ	165	370	296	IPR000108 Neutrophil cytosol factor 2 p67phox	27	292
47	IPR005225 Small GTP-binding protein domain	162	321	297	IPR003968 Potassium channel, voltage dependent, Kv	27	166
48	IPR001314 Peptidase S1A, chymotrypsin-type	150	666	298	IPR001315 Caspase Recruitment	26	136
49	IPR001478 PDZ domain	149	2827	299	IPR018934 RIO-like kinase	26	34
50	IPR017978 GPCR, family 3, C-terminal	148	386	300	IPR008144 Guanylate kinase	26	164
51	IPR003579 Small GTPase superfamily, Rab type	147	292	301	IPR013787 S100/CaBP-9k-type, calcium binding, subdomain	26	41
52	IPR002048 Calcium-binding EF-hand	146	877	302	IPR002366 Defensin propeptide	26	29
53	IPR000337 GPCR, family 3	143	1813	303	IPR002083 MATH	26	126
54	IPR011500 GPCR, family 3, nine cysteines domain	141	182	304	IPR023780 Chromo domain	26	88
55	IPR003593 AAA+ ATPase domain	139	352	305	IPR022755 Zinc finger, double-stranded RNA binding	26	68
56	IPR004073 GPCR, family 3, vomeronasal receptor, type 2	136	1226	306	IPR003054 Type II keratin	26	189
57	IPR020849 Small GTPase superfamily, Ras type	130	259	307	IPR001111 Transforming growth factor-beta, N-terminal	26	35
58	IPR011701 Major facilitator superfamily	128	282	308	IPR016327 Alpha-defensin	26	29
59	IPR019734 Tetratricopeptide repeat	126	1825	309	IPR002971 Major urinary protein	26	341
60	IPR000008 C2 calcium-dependent membrane targeting	124	1117	310	IPR017877 Myb-like domain	26	108
61	IPR001881 EGF-like calcium-binding	123	2540	311	IPR000727 Target SNARE coiled-coil domain	25	161
62	IPR013026 Tetratricopeptide repeat-containing domain	123	338	312	IPR002999 Tudor domain	25	253
63	IPR003578 Small GTPase superfamily, Rho type	122	236	313	IPR001251 CRAL-TRIO domain	25	184
64	IPR001304 C-type lectin	114	806	314	IPR020454 Diacylglycerol/phorbol-ester binding	25	272
65	IPR005821 Ion transport	111	498	315	IPR004841 Amino acid permease domain	25	77
66	IPR014001 Helicase, superfamily 1/2, ATP-binding domain	110	443	316	IPR000421 Coagulation factor 5/8 C-terminal type domain	25	196
67	IPR018029 C2 membrane targeting protein	109	437	317	IPR001594 Zinc finger, DHHC-type, palmitoyltransferase	25	87
68	IPR011598 Helix-loop-helix DNA-binding	109	635	318	IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain	25	47
69	IPR001650 Helicase, C-terminal	107	613	319	IPR001125 Recoverin	25	366
70	IPR000980 SH2 domain	107	1560	320	IPR008145 Guanylate kinase/L-type calcium channel	25	88
71	IPR001128 Cytochrome P450	102	665	321	IPR000157 Toll/interleukin-1 receptor homology (TIR) domain	25	122
72	IPR002401 Cytochrome P450, E-class, group I	101	984	322	IPR002348 Interleukin 1/heparin-binding growth factor	24	203
73	IPR007125 Histone core	101	130	323	IPR010294 ADAM-TS Spacer 1	24	43
74	IPR002403 Cytochrome P450, E-class, group IV	100	663	324	IPR006649 Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type	24	33
75	IPR020846 Major facilitator superfamily domain	98	181	325	IPR001163 Like-Sm ribonucleoprotein (LSM) domain	24	35
76	IPR020479 Homeodomain, metazoa	95	393	326	IPR000082 SEA	24	95
77	IPR000795 Protein synthesis factor, GTP-binding	90	354	327	IPR020477 C2 domain	24	176
78	IPR001965 Zinc finger, PHD-type	90	467	328	IPR006207 Cystine knot, C-terminal	24	69
79	IPR000048 IQ motif, EF-hand binding site	89	1059	329	IPR021128 MARVEL-like domain	24	45
80	IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal	88	181	330	IPR018980 FERM, C-terminal PH-like domain	24	93
81	IPR000387 Protein-tyrosine/Dual-specificity phosphatase	87	259	331	IPR001763 Rhodanese-like	24	137
82	IPR002126 Cadherin	87	5328	332	IPR006028 Gamma-aminobutyric acid A receptor	24	170
83	IPR001660 Sterile alpha motif domain	87	436	333	IPR013655 PAS fold-3	24	53
84	IPR020472 G-protein beta WD-40 repeat	86	567	334	IPR002494 Keratin, high sulphur B2	24	35
85	IPR001870 B30.2/SPRY domain	84	173	335	IPR002968 Alpha-1-microglobulin	24	199
86	IPR019430 7TM GPCR, serpentine receptor class x (Srx)	83	142	336	IPR000086 NUDIX hydrolase domain	24	48
87	IPR003877 SPla/RYanodine receptor SPRY	83	173	337	IPR019750 Band 4.1 family	24	350
88	IPR021129 Sterile alpha motif, type 1	83	216	338	IPR013273 Peptidase M12B, ADAM-TS	24	142
89	IPR013162 CD80-like, immunoglobulin C2-set	81	206	339	IPR018487 Hemopexin/matrixin, repeat	24	265
90	IPR019787 Zinc finger, PHD-finger	81	563	340	IPR001818 Peptidase M10, metallopeptidase	24	37
91	IPR002041 Ran GTPase	81	156	341	IPR000467 G-patch domain	23	131
92	IPR006762 Gtr1/RagA G protein	81	151	342	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	23	77
93	IPR008160 Collagen triple helix repeat	80	958	343	IPR001357 BRCT domain	23	176
94	IPR003597 Immunoglobulin C1-set	78	329	344	IPR003607 Metal-dependent phosphohydrolase, HD domain	23	80
95	IPR011510 Sterile alpha motif, type 2	77	221	345	IPR021190 Peptidase M10A, matrix metallopeptidase	23	171
96	IPR001781 Zinc finger, LIM-type	77	1552	346	IPR001140 ABC transporter, transmembrane domain	23	80
97	IPR000483 Cysteine-rich flanking region, C-terminal	76	227	347	IPR016054 Ly-6 antigen / uPA receptor -like	23	38
98	IPR001810 F-box domain, cyclin-like	76	423	348	IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal	23	41
99	IPR002035 von Willebrand factor, type A	76	746	349	IPR001353 Proteasome, subunit alpha/beta	23	34
100	IPR018355 SPla/RYanodine receptor subgroup	76	154	350	IPR007235 Glycosyl transferase, family 28, C-terminal	23	38
101	IPR001715 Calponin homology domain	75	938	351	IPR000355 Chemokine receptor	23	219
102	IPR006209 EGF-like domain	75	593	352	IPR020067 Frizzled domain	23	129
103	IPR002198 Short-chain dehydrogenase/reductase SDR	72	352	353	IPR001876 Zinc finger, RanBP2-type	23	190
104	IPR016044 Filament	72	109	354	IPR001164 Arf GTPase activating protein	23	378
105	IPR000315 Zinc finger, B-box	70	582	355	IPR000668 Peptidase C1A, papain C-terminal	23	143
106	IPR001440 Tetratricopeptide TPR-1	68	310	356	IPR002017 Spectrin repeat	23	758
107	IPR000219 Dbl homology (DH) domain	68	712	357	IPR000620 Drug/metabolite transporter	23	59
108	IPR000198 Rho GTPase-activating protein domain	67	604	358	IPR001855 Beta defensin type	23	23
109	IPR003958 Transcription factor CBF/NF-Y/archaeal histone	66	86	359	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	23	253
110	IPR000884 Thrombospondin, type 1 repeat	65	1694	360	IPR004865 Sp100	22	55
111	IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding	65	689	361	IPR003034 DNA-binding SAP	22	164
112	IPR006652 Kelch repeat type 1	64	992	362	IPR000313 PWWP	22	270
113	IPR023796 Serpin domain	64	254	363	IPR000834 Peptidase M14, carboxypeptidase A	22	156
114	IPR018248 EF-hand	63	267	364	IPR003903 Ubiquitin interacting motif	22	236
115	IPR003595 Protein-tyrosine phosphatase, catalytic	62	199	365	IPR023210 NADP-dependent oxidoreductase domain	22	50
116	IPR013099 Ion transport 2	62	146	366	IPR002130 Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain	21	253
117	IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain	62	109	367	IPR000591 DEP domain	21	183
118	IPR013968 Polyketide synthase, KR	60	109	368	IPR001024 Lipoxygenase, LH2	21	221
119	IPR000626 Ubiquitin	59	299	369	IPR006552 VWC out	21	175
120	IPR001791 Laminin G domain	59	1299	370	IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase	21	50
121	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	58	1070	371	IPR003008 Tubulin/FtsZ, GTPase domain	21	52
122	IPR017981 GPCR, family 2-like	58	148	372	IPR002477 Peptidoglycan binding-like	21	35
123	IPR011705 BTB/Kelch-associated	58	234	373	IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	21	94
124	IPR006888 Cor1/Xlr/Xmr family	58	86	374	IPR001134 Netrin domain	21	27
125	IPR019955 Ubiquitin supergroup	57	157	375	IPR001060 Fps/Fes/Fer/CIP4 homology	21	225
126	IPR002286 P2 purinoceptor	57	446	376	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	21	44
127	IPR002347 Glucose/ribitol dehydrogenase	57	484	377	IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	21	101
128	IPR003879 Butyrophylin-like	57	472	378	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	21	206
129	IPR000436 Sushi/SCR/CCP	57	2185	379	IPR002893 Zinc finger, MYND-type	21	106
130	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	57	263	380	IPR000558 Histone H2B	20	159
131	IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote	56	228	381	IPR000867 Insulin-like growth factor-binding protein, IGFBP	20	50
132	IPR011497 Protease inhibitor, Kazal-type	56	166	382	IPR013517 FG-GAP	20	85
133	IPR003959 ATPase, AAA-type, core	55	118	383	IPR000217 Tubulin	20	216
134	IPR001590 Peptidase M12B, ADAM/reprolysin	55	249	384	IPR013092 Connexin, N-terminal	20	67
135	IPR003439 ABC transporter-like	54	320	385	IPR000175 Sodium:neurotransmitter symporter	20	440
136	IPR002870 Peptidase M12B, propeptide	54	126	386	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	20	328
137	IPR010440 Lipopolysaccharide kinase	54	111	387	IPR001159 Double-stranded RNA-binding	20	350
138	IPR009071 High mobility group, superfamily	53	630	388	IPR004839 Aminotransferase, class I/classII	20	44
139	IPR013111 EGF, extracellular	53	561	389	IPR000500 Connexin	20	194
140	IPR000372 Leucine-rich repeat-containing N-terminal	53	258	390	IPR004057 Epsilon tubulin	20	144
141	IPR005828 General substrate transporter	52	116	391	IPR013025 Ribosomal protein L25/L23	20	20
142	IPR001623 Heat shock protein DnaJ, N-terminal	52	336	392	IPR003953 Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal	20	58
143	IPR018108 Mitochondrial substrate/solute carrier	52	605	393	IPR001675 Glycosyl transferase, family 29	20	46
144	IPR019426 7TM GPCR, serpentine receptor class v (Srv)	52	71	394	IPR019570 Gap junction protein, cysteine-rich domain	20	32
145	IPR000859 CUB	51	1022	395	IPR023412 Ribonuclease A, domain	20	52
146	IPR003131 Potassium channel, voltage dependent, Kv, tetramerisation	50	100	396	IPR015590 Aldehyde dehydrogenase domain	20	44
147	IPR004031 PMP-22/EMP/MP20/Claudin	50	78	397	IPR001932 Protein phosphatase 2C-like	20	95
148	IPR019009 Signal recognition particle receptor, beta subunit	50	92	398	IPR006080 Beta defensin/Neutrophil defensin	19	22
149	IPR004827 Basic-leucine zipper domain	50	280	399	IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase	19	60
150	IPR002397 Cytochrome P450, B-class	50	262	400	IPR001147 Ribosomal protein L21e	19	21
151	IPR000536 Nuclear hormone receptor, ligand-binding, core	49	278	401	IPR019956 Ubiquitin subgroup	19	100
152	IPR000608 Ubiquitin-conjugating enzyme, E2	49	210	402	IPR023088 3'5'-cyclic nucleotide phosphodiesterase	19	504
153	IPR001811 Chemokine interleukin-8-like domain	49	131	403	IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain	19	164
154	IPR001202 WW/Rsp5/WWP	49	662	404	IPR005817 Wnt	19	237
155	IPR000571 Zinc finger, CCCH-type	49	413	405	IPR002575 Aminoglycoside phosphotransferase	19	34
156	IPR000299 FERM domain	48	173	406	IPR010456 Ribosomal L11 methyltransferase, PrmA	19	43
157	IPR001683 Phox homologous domain	48	316	407	IPR004161 Translation elongation factor EFTu/EF1A, domain 2	19	38
158	IPR000832 GPCR, family 2, secretin-like	47	821	408	IPR013201 Proteinase inhibitor I29, cathepsin propeptide	19	46
159	IPR001723 Steroid hormone receptor	47	638	409	IPR018316 Tubulin/FtsZ, 2-layer sandwich domain	19	38
160	IPR019749 Band 4.1 domain	47	158	410	IPR004182 GRAM	19	124
161	IPR001628 Zinc finger, nuclear hormone receptor-type	47	1036	411	IPR008197 Whey acidic protein, 4-disulphide core	19	83
162	IPR013094 Alpha/beta hydrolase fold-3	47	93	412	IPR002967 Delta tubulin	19	134
163	IPR001214 SET domain	47	363	413	IPR000408 Regulator of chromosome condensation, RCC1	19	853
164	IPR000225 Armadillo	47	1247	414	IPR003594 ATPase-like, ATP-binding domain	19	49
165	IPR002172 Low-density lipoprotein (LDL) receptor class A repeat	46	1422	415	IPR005633 Ribosomal protein L23/L25, N-terminal	19	19
166	IPR000961 AGC-kinase, C-terminal	45	125	416	IPR006076 FAD dependent oxidoreductase	19	52
167	IPR000340 Dual specificity phosphatase, catalytic domain	45	103	417	IPR000248 Angiotensin II receptor	19	181
168	IPR005834 Haloacid dehalogenase-like hydrolase	45	100	418	IPR006052 Tumour necrosis factor	19	90
169	IPR001752 Kinesin, motor domain	45	710	419	IPR016293 Peptidase M10A, matrix metallopeptidase, stromelysin type	19	27
170	IPR001005 SANT/Myb domain	45	325	420	IPR010909 PLAC	19	58
171	IPR019748 FERM central domain	44	149	421	IPR005913 dTDP-4-dehydrorhamnose reductase	19	36
172	IPR003095 Heat shock protein DnaJ	44	310	422	IPR004012 RUN	19	148
173	IPR003309 Transcription regulator SCAN	44	337	423	IPR013519 Integrin alpha beta-propellor	19	246
174	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	44	649	424	IPR003869 Polysaccharide biosynthesis protein CapD-like	19	42
175	IPR002119 Histone H2A	43	276	425	IPR019577 SPARC/Testican, calcium-binding domain	19	48
176	IPR000863 Sulfotransferase domain	43	85	426	IPR007502 Helicase-associated domain	18	78
177	IPR001766 Transcription factor, fork head	43	523	427	IPR000433 Zinc finger, ZZ-type	18	204
178	IPR006935 Helicase/UvrB domain	43	91	428	IPR004156 Organic anion transporter polypeptide OATP	18	74
179	IPR011616 bZIP transcription factor, bZIP-1	42	124	429	IPR004033 UbiE/COQ5 methyltransferase	18	34
180	IPR013105 Tetratricopeptide TPR2	42	94	430	IPR001846 von Willebrand factor, type D domain	18	247
181	IPR006029 Neurotransmitter-gated ion-channel transmembrane domain	42	90	431	IPR013149 Alcohol dehydrogenase, C-terminal	18	29
182	IPR006586 ADAM, cysteine-rich	42	180	432	IPR000798 Ezrin/radixin/moesin family	18	309
183	IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain	42	132	433	IPR002928 Myosin tail	18	51
184	IPR006201 Neurotransmitter-gated ion-channel	42	341	434	IPR003655 Krueppel-associated box-related	18	36
185	IPR017096 Kelch-like protein, gigaxonin	42	73	435	IPR003124 WH2 domain	18	145
186	IPR011700 Basic leucine zipper	42	121	436	IPR003137 Protease-associated domain, PA	18	31
187	IPR006202 Neurotransmitter-gated ion-channel ligand-binding	42	79	437	IPR006553 Leucine-rich repeat, cysteine-containing subtype	18	246
188	IPR000159 Ras-association	41	299	438	IPR001508 NMDA receptor	18	201
189	IPR006020 Phosphotyrosine interaction domain	41	394	439	IPR009038 GOLD	18	56
190	IPR002353 Type II antifreeze protein	41	310	440	IPR021743 Keratin-associated matrix	18	21
191	IPR001487 Bromodomain	41	1071	441	IPR004014 ATPase, P-type cation-transporter, N-terminal	18	99
192	IPR013122 Polycystin cation channel, PKD1/PKD2	41	134	442	IPR002453 Beta tubulin	18	168
193	IPR024156 Small GTPase superfamily, ARF type	41	69	443	IPR001320 Ionotropic glutamate receptor	18	106
194	IPR003659 Plexin/semaphorin/integrin	40	141	444	IPR007593 Interferon-induced transmembrane protein	18	27
195	IPR015420 Peptidase S1A, nudel	40	63	445	IPR002452 Alpha tubulin	18	173
196	IPR011498 Kelch repeat type 2	39	133	446	IPR013120 Male sterility, NAD-binding	18	43
197	IPR004087 K Homology domain	39	256	447	IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain	18	123
198	IPR000195 Rab-GTPase-TBC domain	39	284	448	IPR001194 DENN	18	198
199	IPR000611 Neuropeptide Y receptor	39	365	449	IPR004148 BAR domain	18	127
200	IPR001609 Myosin head, motor domain	39	750	450	IPR013649 Integrin alpha-2	18	51
201	IPR002350 Proteinase inhibitor I1, Kazal	38	261	451	IPR001638 Extracellular solute-binding protein, family 3	18	53
202	IPR004088 K Homology domain, type 1	38	497	452	IPR000413 Integrin alpha chain	18	374
203	IPR017892 Protein kinase, C-terminal	37	110	453	IPR001148 Alpha carbonic anhydrase	18	71
204	IPR001839 Transforming growth factor-beta, C-terminal	37	88	454	IPR015898 G-protein gamma-like domain	18	140
205	IPR001496 SOCS protein, C-terminal	37	257	455	IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant	18	38
206	IPR001526 CD59 antigen	37	68	456	IPR000998 MAM domain	18	360
207	IPR000357 HEAT	37	159	457	IPR000095 PAK-box/P21-Rho-binding	18	128
208	IPR017455 Zinc finger, FYVE-related	37	79	458	IPR019594 Glutamate receptor, L-glutamate/glycine-binding	18	106
209	IPR001762 Blood coagulation inhibitor, Disintegrin	36	347	459	IPR013217 Methyltransferase type 12	18	26
210	IPR008250 ATPase, P-type, ATPase-associated domain	36	99	460	IPR001507 Zona pellucida sperm-binding protein	17	92
211	IPR001039 MHC class I, alpha chain, alpha1/alpha2	36	334	461	IPR001565 Synaptotagmin	17	143
212	IPR001509 NAD-dependent epimerase/dehydratase	36	72	462	IPR006195 Aminoacyl-tRNA synthetase, class II	17	27
213	IPR005135 Endonuclease/exonuclease/phosphatase	36	93	463	IPR011489 EMI domain	17	100
214	IPR020422 Dual specificity phosphatase, subgroup, catalytic domain	36	151	464	IPR006081 Mammalian defensins	17	19
215	IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain	36	39	465	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	17	118
216	IPR001007 von Willebrand factor, type C	36	552	466	IPR000716 Thyroglobulin type-1	17	138
217	IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal	36	236	467	IPR018933 Netrin module, non-TIMP type	17	40
218	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	36	547	468	IPR011016 Zinc finger, RING-CH-type	17	45
219	IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain	36	78	469	IPR003118 Pointed domain	17	88
220	IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family	36	220	470	IPR005123 Oxoglutarate/iron-dependent oxygenase	17	35
221	IPR013216 Methyltransferase type 11	35	92	471	IPR020471 Aldo/keto reductase subgroup	17	141
222	IPR006574 SPRY-associated	35	62	472	IPR000164 Histone H3	17	178
223	IPR014014 RNA helicase, DEAD-box type, Q motif	35	65	473	IPR006212 Furin-like repeat	17	121
224	IPR003091 Voltage-dependent potassium channel	35	491	474	IPR001401 Dynamin, GTPase domain	17	92
225	IPR000073 Alpha/beta hydrolase fold-1	35	152	475	IPR002123 Phospholipid/glycerol acyltransferase	17	96
226	IPR011704 ATPase, dynein-related, AAA domain	35	84	476	IPR007052 CS-like domain	17	36
227	IPR000342 Regulator of G protein signalling	35	587	477	IPR000826 Formyl/methionyl peptide receptor	17	125
228	IPR000488 Death	35	219	478	IPR013057 Amino acid transporter, transmembrane	17	57
229	IPR002049 EGF-like, laminin	35	1294	479	IPR001427 Ribonuclease A	17	93
230	IPR000953 Chromo domain/shadow	34	204	480	IPR001494 Importin-beta, N-terminal	17	98
231	IPR013766 Thioredoxin domain	34	90	481	IPR001064 Beta/gamma crystallin	17	454
232	IPR013164 Cadherin, N-terminal	34	64	482	IPR003890 MIF4G-like, type 3	17	90
233	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	34	241	483	IPR007848 Methyltransferase small	17	45
234	IPR000010 Proteinase inhibitor I25, cystatin	34	137	484	IPR011619 Ferrous iron transport protein B, N-terminal	17	28
235	IPR000182 GNAT domain	33	134	485	IPR000644 Cystathionine beta-synthase, core	17	184
236	IPR022617 Small ubiquitin-related modifier, SUMO	33	110	486	IPR022775 AP complex, mu/sigma subunit	17	35
237	IPR000014 PAS	33	229	487	IPR013657 UAA transporter	17	40
238	IPR002909 Cell surface receptor IPT/TIG	33	297	488	IPR011709 Domain of unknown function DUF1605	17	36
239	IPR002190 MAGE protein	33	126	489	IPR021072 Melanoma associated antigen, MAGE, N-terminal	17	26
240	IPR000330 SNF2-related	33	93	490	IPR006620 Prolyl 4-hydroxylase, alpha subunit	16	30
241	IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain	33	66	491	IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like	16	50
242	IPR000047 Helix-turn-helix motif	33	96	492	IPR005112 dDENN	16	177
243	IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45	33	36	493	IPR002867 Zinc finger, C6HC-type	16	102
244	IPR002957 Keratin, type I	33	193	494	IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain	16	101
245	IPR000595 Cyclic nucleotide-binding domain	33	314	495	IPR006068 ATPase, P-type cation-transporter, C-terminal	16	40
246	IPR000772 Ricin B lectin domain	32	145	496	IPR000717 Proteasome component (PCI) domain	16	76
247	IPR003347 JmjC domain	32	267	497	IPR003915 Polycystic kidney disease type 2 protein	16	144
248	IPR013767 PAS fold	32	81	498	IPR002659 Glycosyl transferase, family 31	16	23
249	IPR013763 Cyclin-like	32	92	499	IPR003280 Two pore domain potassium channel	16	44
250	IPR006671 Cyclin, N-terminal	32	66	500	IPR001699 Transcription factor, T-box	16	317

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