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Human vs Wallaby BlastZ alignments

Human (Homo sapiens, GRCh37) and Wallaby (Macropus eugenii, Meug_1.0) were aligned using the BlastZ alignment algorithm (Schwartz S et al., Genome Res.;13(1):103-7, Kent WJ et al., Proc Natl Acad Sci U S A., 2003;100(20):11484-9) in Ensembl release 55. Human was used as the reference species. After running BlastZ , the raw BlastZ alignment blocks are chained according to their location in both genomes. During the final netting process, the best sub-chain is chosen in each region on the reference species.

Full list of pairwise alignments

Configuration parameters

Gap open penalty (O) 400
Gap extend penalty (E) 30
HSP threshold (K) 3000
Threshold for gapped extension (L) 3000
Threshold for alignments between gapped alignment blocks (H) 2200
Masking count (M) 50
Seed and Transition value (T) 1
Scoring matrix (Q) Default

Results

Number of alignment blocks: 578119

Genome coverage(bp) Coding exon coverage (bp)
Human
202,002,924 out of 3,098,825,702 28,441,149 out of 35,483,623
Wallaby
176,573,095 out of 2,955,773,937 20,746,505 out of 25,589,509